Video: Latest Betting Including Villa v Man City
Of the top four Manchester City arguably face the toughest challenge. Despite Aston Villa's lowly league position, they have a new striker in Darren Bent, no doubt with some points to prove.
So many score draws last weekend, which meant another big payout on Goals Galore and this week's legend, Gary Owen, predicts more of the same, although it could be time for King Kenny to start earning points as Liverpool visit Wolverhampton.
High flying Bolton, meanwhile, have given Chelsea some scares in the past, could it be the same again, or will the wounded South Londoners get their season back on track?
Predictions and more for all this weekend's Premier League ties and of course the best odds on Betfred.com